STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amtRAMTR PROTEIN. (222 aa)    
Predicted Functional Partners:
glnK
Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
  
  
 0.988
amtB
LOW AFFINITY AMMONIUM UPTAKE PROTEIN.
   
  
 0.965
glnD
PROBABLE PROTEIN-PII URIDYLYLTRANSFERASE; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism (By simil [...]
      
 0.852
glnA
GLUTAMINE SYNTHETASE I.
      
 0.798
Cgl0864
Conserved hypothetical protein.
  
    0.705
gltB
GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU.
      
 0.689
acnR
TRANSCRIPTIONAL REGULATOR, TETR FAMILY; AcnR negatively controls the expression of the aconitase gene acn. Binds to the imperfect inverted repeat in the acn promoter region.
  
   
 0.680
glnE
GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
      
 0.648
codA
CREATININE DEAMINASE.
   
  
 0.612
Cgl2612
Bacterial regulatory protein, TetR family.
   
  
 0.608
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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