node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0682 | rpf2 | cg0784 | cg1037 | PUTATIVE CELL WALL-ASSOCIATED HYDROLASE. | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.711 |
Cgl0908 | Cgl0912 | cg1035 | cg1040 | TatD related DNase. | ATPase component of ABC transporters with duplicated ATPase domains. | 0.537 |
Cgl0908 | ispE | cg1035 | cg1039 | TatD related DNase. | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.814 |
Cgl0908 | ksgA | cg1035 | cg1038 | TatD related DNase. | PUTATIVE DIMETHYLADENOSINE TRANSFERASE; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.933 |
Cgl0908 | rpf2 | cg1035 | cg1037 | TatD related DNase. | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.834 |
Cgl0912 | Cgl0908 | cg1040 | cg1035 | ATPase component of ABC transporters with duplicated ATPase domains. | TatD related DNase. | 0.537 |
Cgl0912 | ispE | cg1040 | cg1039 | ATPase component of ABC transporters with duplicated ATPase domains. | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.869 |
Cgl0912 | ksgA | cg1040 | cg1038 | ATPase component of ABC transporters with duplicated ATPase domains. | PUTATIVE DIMETHYLADENOSINE TRANSFERASE; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.950 |
Cgl0912 | pdxK | cg1040 | cg1041 | ATPase component of ABC transporters with duplicated ATPase domains. | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | 0.939 |
Cgl0912 | rpf2 | cg1040 | cg1037 | ATPase component of ABC transporters with duplicated ATPase domains. | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.907 |
Cgl1538 | rpf2 | cg1735 | cg1037 | Secreted cell wall-associated hydrolase (invasion-associated protein). | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.635 |
glxR | ramA | cg0350 | cg2831 | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | Bacterial regulatory protein, LuxR family; RamA is a master regulator of acetate metabolism. It positively controls the expression of acnA, aceA, aceB, ack, pta and ramB genes in the presence of acetate. RamA is also a positive regulator of rpf2 gene expression during growth on glucose as the sole carbon source. | 0.984 |
glxR | ramB | cg0350 | cg0444 | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | Transcriptional regulator, MerR family; During growth on glucose, RamB negatively controls the expression of aceA, aceB, ack and pta genes which are involved in acetate metabolism. RamB is also a negative regulator of rpf2 gene expression during growth on acetate as the sole carbon source ; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.981 |
glxR | rpf2 | cg0350 | cg1037 | TRANSCRIPTIONAL REGULATOR, CRP/FNR FAMILY; Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Involved in the regulation of gntP and gntK genes, which are involved in gluconate metabolism. May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes. It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole [...] | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.631 |
ispE | Cgl0908 | cg1039 | cg1035 | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | TatD related DNase. | 0.814 |
ispE | Cgl0912 | cg1039 | cg1040 | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | ATPase component of ABC transporters with duplicated ATPase domains. | 0.869 |
ispE | ksgA | cg1039 | cg1038 | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | PUTATIVE DIMETHYLADENOSINE TRANSFERASE; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.998 |
ispE | pdxK | cg1039 | cg1041 | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | 0.775 |
ispE | rpf2 | cg1039 | cg1037 | PUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Putative RPF2 precursor, secreted protein; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity). | 0.882 |
ksgA | Cgl0908 | cg1038 | cg1035 | PUTATIVE DIMETHYLADENOSINE TRANSFERASE; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | TatD related DNase. | 0.933 |