STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnRTRANSCRIPTIONAL REGULATOR, TETR FAMILY; AcnR negatively controls the expression of the aconitase gene acn. Binds to the imperfect inverted repeat in the acn promoter region. (188 aa)    
Predicted Functional Partners:
ribX
Putative membrane protein-C. ammoniagenes RibX homolog.
  
    0.748
Cgl1542
Glutamine amidotransferase domain.
  
    0.727
Cgl2374
Putative membrane protein.
  
     0.706
Cgl0774
Conserved hypothetical protein.
  
     0.697
ripA
AraC-type DNA-binding domain-containing protein; Under iron limitation, RipA negatively controls the expression of the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes. Binds to the consensus sequence in the promoter region.
  
   
 0.684
amtR
AMTR PROTEIN.
  
   
 0.680
Cgl2498
Putative membrane protein.
  
     0.679
acn
ACONITASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2- methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity). ECO:0000250|UniProtKB:Q8ZP52, ; Belongs to the aconitase/IPM isomerase family.
  
    0.661
Cgl1322
Putative secreted protein.
  
     0.659
Cgl2179
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.659
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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