STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnRHTH-type transcriptional repressor AcnR; AcnR negatively controls the expression of the aconitase gene acn. Binds to the imperfect inverted repeat in the acn promoter region (188 aa)    
Predicted Functional Partners:
acn
Aconitate hydratase A; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis- aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity); Belongs to the aconitase/IPM isomerase family
  
  
 0.916
Cgl1542
GMP synthase-Glutamine amidotransferase domain; Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group
  
    0.772
ribX
annotation not available
  
     0.723
Cgl1906
annotation not available
  
     0.644
Cgl1961
annotation not available
  
     0.638
cg0496
annotation not available
  
    0.607
ripA
HTH-type transcriptional regulator RipA; Under iron limitation, RipA negatively controls the expression of the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes. Binds to the consensus sequence in the promoter region
      
 0.594
Cgl2374
annotation not available
  
     0.592
Cgl2612
annotation not available
      
 0.591
Cgl2949
annotation not available
  
     0.591
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum ATCC13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (12%) [HD]