STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFOrotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (278 aa)    
Predicted Functional Partners:
pyrE
OROTATE PHOSPHORIBOSYLTRANSFERASE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.999
carB
PUTATIVE CARBAMOYL-PHOSPHATE SYNTHASE SUBUNIT.
  
 0.993
upp
PUTATIVE URACIL PHOSPHORIBOSYLTRANSFERASE; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.992
pyrR
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
  
 
 0.990
carA
CARBAMOYL PHOSPHATE SYNTHASE SMALL SUBUNIT; Belongs to the CarA family.
 
  
 0.978
pyrB
ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.977
pyrH
UMP-KINASE; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.953
pyrC
PUTATIVE DIHYDROOROTASE; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.949
pyrD
DIHYDROOROTATE DEHYDROGENASE; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.946
Cgl0328
PROBABLE 5'-NUCLEOTIDASE PRECURSOR; Belongs to the 5'-nucleotidase family.
    
  0.900
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.