STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (152 aa)    
Predicted Functional Partners:
ftsZ
Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.998
ftsQ
Cell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
  
 0.933
Cgl2153
Pyridoxal-5'-phosphate dependent enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
  
  
 0.929
ftsW
Bacterial cell division membrane protein; Belongs to the SEDS family.
 
   
 0.909
Cgl2151
Putative membrane protein.
  
  
 0.907
ftsI
PENICILLIN-BINDING PROTEIN 2X.
     
 0.854
Cgl2150
Cell division initiation protein-Antigen 84 homolog.
  
  
 0.799
Cgl2154
Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity.
  
  
 0.797
Cgl1381
Hypothetical protein predicted by Glimmer/Critica.
  
 
 0.793
ftsK
CELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family.
   
  
 0.724
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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