STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrAPEPTIDE METHIONINE SULFOXIDE REDUCTASE; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (217 aa)    
Predicted Functional Partners:
Cgl1898
PEPTIDE METHIONINE SULFOXIDE REDUCTASE-RELATED PROTEIN; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.995
mrx1
Glutaredoxin or related protein; Involved in defense against toxic arsenate. Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; functions as a monothiol mixed disulfide reductase and is recycled by a second mycothiol forming mycothione which in turn is reduced in a NADPH-dependent manner.
  
 
 0.972
polA
DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.854
nrdH
PUTATIVE GLUTAREDOXIN NRDH.
  
 
 0.846
Cgl0294
THIOREDOXIN-RELATED PROTEIN, secreted.
  
 0.799
Cgl0439
Secreted thiol-disulfide isomerase or thioredoxin.
  
 0.795
cg3289
Thiol-disulfide isomerase or thioredoxin.
   
 0.794
mca
Uncharacterized proteins, LmbE homolog; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
  
 0.773
trxB
THIOREDOXIN REDUCTASE.
  
  
 0.760
gor
PUTATIVE GLUTATHIONE REDUCTASE.
  
  
 0.751
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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