STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagIPROBABLE GENTISATE 1,2-DIOXYGENASE OXIDOREDUCTASE. (375 aa)    
Predicted Functional Partners:
Cgl3021
Conserved hypothetical protein.
 
  
 0.998
Cgl3026
Aromatic-ring hydroxylase (flavoprotein monooxygenase); Catalyzes the NADH-dependent conversion of 3-hydroxybenzoate to gentisate (2,5-dihydroxybenzoate). Is involved in the utilization of 3-hydroxybenzoate as a sole source of carbon and energy for C.glutamicum growth. Displays a high preference for NADH over NADPH as cosubstrate. Is not active with 4-hydroxybenzoate, salicylate, protocatechuate or benzoate as substrates.
 
  
 0.963
benK2
Putative benzoate transport protein; Transport of gentisate (2,5-dihydroxybenzoate) into the cell. Does not transport 3-hydroxybenzoate or benzoate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
 
  
 0.914
hpaG
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway); PUTATIVE BIFUNCTIONAL ENZYME 2-HYDROXYHEPTA-2,4-DIENE-1, 7-DIOATESOMERASE5-CARBOXYMETHYL-2-OXO-HEX-3.
   
 0.906
Cgl3024
Transcriptional regulator; Unnamed protein product.
 
    0.781
Cgl0967
Predicted esterase, membrane protein.
  
  
 0.707
catC
MUCONOLACTONE ISOMERASE; Belongs to the muconolactone Delta-isomerase family.
   
  
 0.603
benC
BENZOATE DIOXYGENASE REDUCTASE.
  
  
 0.480
Cgl0552
Pyruvate phosphate dikinase, PEP/pyruvate binding.
   
  
 0.413
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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