clpC protein (Thermosynechococcus elongatus)

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Score

clpC

ATP-dependent Clp protease regulatory subunit (824 aa)

Predicted Functional Partners:

dnaK2

0.976

grpE

0.969

dnaK3

0.960

dnaK1

0.958

clpP

0.957

tll0790

0.940

tlr0324

0.932

clpP1

0.921

clpP2

0.919

clpS

0.903

Your Current Organism:

Thermosynechococcus elongatus

NCBI taxonomy Id: 197221
Other names: T. elongatus, T. elongatus BP-1, Thermosynechococcus, Thermosynechococcus elongatus, Thermosynechococcus elongatus BP-1, Thermosynechococcus elongatus str. BP-1, Thermosynechococcus elongatus strain BP-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
clpC	clpP	tll0307	tll1759	ATP-dependent Clp protease regulatory subunit	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	0.957
clpC	clpP1	tll0307	tlr0509	ATP-dependent Clp protease regulatory subunit	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	0.921
clpC	clpP2	tll0307	tlr1071	ATP-dependent Clp protease regulatory subunit	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	0.919
clpC	clpS	tll0307	tsr1087	ATP-dependent Clp protease regulatory subunit	ATP-dependent Clp protease adaptor; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	0.903
clpC	dnaK1	tll0307	tll0791	ATP-dependent Clp protease regulatory subunit	Molecular chaperone DnaK; Acts as a chaperone	0.958
clpC	dnaK2	tll0307	tlr1733	ATP-dependent Clp protease regulatory subunit	Molecular chaperone DnaK; Acts as a chaperone	0.976
clpC	dnaK3	tll0307	tll2150	ATP-dependent Clp protease regulatory subunit	Molecular chaperone DnaK; Acts as a chaperone	0.960
clpC	grpE	tll0307	tlr1314	ATP-dependent Clp protease regulatory subunit	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depe [...]	0.969
clpC	tll0790	tll0307	tll0790	ATP-dependent Clp protease regulatory subunit	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.940
clpC	tlr0324	tll0307	tlr0324	ATP-dependent Clp protease regulatory subunit	Hypothetical protein	0.932
clpP	clpC	tll1759	tll0307	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	ATP-dependent Clp protease regulatory subunit	0.957
clpP	clpP2	tll1759	tlr1071	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	0.504
clpP	dnaK1	tll1759	tll0791	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.556
clpP	dnaK2	tll1759	tlr1733	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.677
clpP	dnaK3	tll1759	tll2150	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.684
clpP	grpE	tll1759	tlr1314	ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depe [...]	0.678
clpP1	clpC	tlr0509	tll0307	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	ATP-dependent Clp protease regulatory subunit	0.921
clpP1	dnaK1	tlr0509	tll0791	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.476
clpP1	dnaK2	tlr0509	tlr1733	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.520
clpP1	dnaK3	tlr0509	tll2150	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	Molecular chaperone DnaK; Acts as a chaperone	0.483

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