node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpC | clpP | tll0307 | tll1759 | ATP-dependent Clp protease regulatory subunit | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | 0.957 |
clpC | clpP1 | tll0307 | tlr0509 | ATP-dependent Clp protease regulatory subunit | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | 0.921 |
clpC | clpP2 | tll0307 | tlr1071 | ATP-dependent Clp protease regulatory subunit | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | 0.919 |
clpC | clpS | tll0307 | tsr1087 | ATP-dependent Clp protease regulatory subunit | ATP-dependent Clp protease adaptor; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation | 0.903 |
clpC | dnaK1 | tll0307 | tll0791 | ATP-dependent Clp protease regulatory subunit | Molecular chaperone DnaK; Acts as a chaperone | 0.958 |
clpC | dnaK2 | tll0307 | tlr1733 | ATP-dependent Clp protease regulatory subunit | Molecular chaperone DnaK; Acts as a chaperone | 0.976 |
clpC | dnaK3 | tll0307 | tll2150 | ATP-dependent Clp protease regulatory subunit | Molecular chaperone DnaK; Acts as a chaperone | 0.960 |
clpC | grpE | tll0307 | tlr1314 | ATP-dependent Clp protease regulatory subunit | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depe [...] | 0.969 |
clpC | tll0790 | tll0307 | tll0790 | ATP-dependent Clp protease regulatory subunit | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.940 |
clpC | tlr0324 | tll0307 | tlr0324 | ATP-dependent Clp protease regulatory subunit | Hypothetical protein | 0.932 |
clpP | clpC | tll1759 | tll0307 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | ATP-dependent Clp protease regulatory subunit | 0.957 |
clpP | clpP2 | tll1759 | tlr1071 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | 0.504 |
clpP | dnaK1 | tll1759 | tll0791 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.556 |
clpP | dnaK2 | tll1759 | tlr1733 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.677 |
clpP | dnaK3 | tll1759 | tll2150 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.684 |
clpP | grpE | tll1759 | tlr1314 | ATP-dependent Clp protease-like protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depe [...] | 0.678 |
clpP1 | clpC | tlr0509 | tll0307 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | ATP-dependent Clp protease regulatory subunit | 0.921 |
clpP1 | dnaK1 | tlr0509 | tll0791 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.476 |
clpP1 | dnaK2 | tlr0509 | tlr1733 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.520 |
clpP1 | dnaK3 | tlr0509 | tll2150 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | Molecular chaperone DnaK; Acts as a chaperone | 0.483 |