node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
folE | folK | gene:10747907 | gene:10746759 | GTP cyclohydrolase I; ORF_ID:tll1309. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | 0.997 |
folE | folP | gene:10747907 | gene:10748122 | GTP cyclohydrolase I; ORF_ID:tll1309. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.917 |
folE | moaA | gene:10747907 | gene:10747961 | GTP cyclohydrolase I; ORF_ID:tll1309. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.908 |
folE | ribA | gene:10747907 | gene:10748331 | GTP cyclohydrolase I; ORF_ID:tll1309. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.947 |
folE | tll0584 | gene:10747907 | gene:10747174 | GTP cyclohydrolase I; ORF_ID:tll1309. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |
folE | tll0747 | gene:10747907 | gene:10747337 | GTP cyclohydrolase I; ORF_ID:tll1309. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.968 |
folE | tll1095 | gene:10747907 | gene:10747691 | GTP cyclohydrolase I; ORF_ID:tll1309. | 6-pyruvoyl-tetrahydropterin synthase; ORF_ID:tll1095. | 0.979 |
folE | tll2275 | gene:10747907 | gene:10748892 | GTP cyclohydrolase I; ORF_ID:tll1309. | Pyruvate kinase; ORF_ID:tll2275; Belongs to the pyruvate kinase family. | 0.811 |
folE | tlr0267 | gene:10747907 | gene:10746850 | GTP cyclohydrolase I; ORF_ID:tll1309. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.836 |
folE | tlr0516 | gene:10747907 | gene:10747105 | GTP cyclohydrolase I; ORF_ID:tll1309. | Pyruvate kinase; ORF_ID:tlr0516; Belongs to the pyruvate kinase family. | 0.803 |
folK | folE | gene:10746759 | gene:10747907 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | GTP cyclohydrolase I; ORF_ID:tll1309. | 0.997 |
folK | folP | gene:10746759 | gene:10748122 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folK | ribA | gene:10746759 | gene:10748331 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.565 |
folK | tll0747 | gene:10746759 | gene:10747337 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.998 |
folP | folE | gene:10748122 | gene:10747907 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I; ORF_ID:tll1309. | 0.917 |
folP | folK | gene:10748122 | gene:10746759 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; ORF_ID:tll0178. | 0.999 |
folP | ribA | gene:10748122 | gene:10748331 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.402 |
folP | tll0747 | gene:10748122 | gene:10747337 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.991 |
moaA | folE | gene:10747961 | gene:10747907 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | GTP cyclohydrolase I; ORF_ID:tll1309. | 0.908 |
moaA | ribA | gene:10747961 | gene:10748331 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.901 |