node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisIE | tll1358 | gene:10746815 | gene:10747956 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | ORF_ID:tll1358; probable glycosyl transferase. | 0.591 |
hisIE | trpA | gene:10746815 | gene:10747028 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.679 |
hisIE | trpB | gene:10746815 | gene:10749096 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.580 |
hisIE | trpC | gene:10746815 | gene:10747288 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Indole-3-glycerol phosphate synthase; ORF_ID:tll0698; Belongs to the TrpC family. | 0.577 |
hisIE | trpD | gene:10746815 | gene:10748318 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.591 |
hisIE | trpE | gene:10746815 | gene:10746868 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthase component I; ORF_ID:tlr0285. | 0.456 |
hisIE | trpE-2 | gene:10746815 | gene:10748274 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.585 |
hisIE | trpF | gene:10746815 | gene:10748889 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:tll2272; Belongs to the TrpF family. | 0.682 |
hisIE | trpG | gene:10746815 | gene:10748071 | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthase component II; ORF_ID:tlr1471. | 0.525 |
pth | trpF | gene:10747982 | gene:10748889 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:tll2272; Belongs to the TrpF family. | 0.606 |
tll1358 | hisIE | gene:10747956 | gene:10746815 | ORF_ID:tll1358; probable glycosyl transferase. | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | 0.591 |
tll1358 | trpA | gene:10747956 | gene:10747028 | ORF_ID:tll1358; probable glycosyl transferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.943 |
tll1358 | trpB | gene:10747956 | gene:10749096 | ORF_ID:tll1358; probable glycosyl transferase. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.917 |
tll1358 | trpC | gene:10747956 | gene:10747288 | ORF_ID:tll1358; probable glycosyl transferase. | Indole-3-glycerol phosphate synthase; ORF_ID:tll0698; Belongs to the TrpC family. | 0.946 |
tll1358 | trpE | gene:10747956 | gene:10746868 | ORF_ID:tll1358; probable glycosyl transferase. | Anthranilate synthase component I; ORF_ID:tlr0285. | 0.969 |
tll1358 | trpE-2 | gene:10747956 | gene:10748274 | ORF_ID:tll1358; probable glycosyl transferase. | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.972 |
tll1358 | trpF | gene:10747956 | gene:10748889 | ORF_ID:tll1358; probable glycosyl transferase. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:tll2272; Belongs to the TrpF family. | 0.940 |
tll1358 | trpG | gene:10747956 | gene:10748071 | ORF_ID:tll1358; probable glycosyl transferase. | Anthranilate synthase component II; ORF_ID:tlr1471. | 0.940 |
trpA | hisIE | gene:10747028 | gene:10746815 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Histidine biosynthesis bifunctional protein; ORF_ID:tll0233; In the C-terminal section; belongs to the PRA-PH family. | 0.679 |
trpA | tll1358 | gene:10747028 | gene:10747956 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | ORF_ID:tll1358; probable glycosyl transferase. | 0.943 |