node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | purB | gene:10749038 | gene:10748434 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.875 |
guaA | purH | gene:10749038 | gene:10748148 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | 0.853 |
guaA | tll0054 | gene:10749038 | gene:10746632 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
guaA | tll1786 | gene:10749038 | gene:10748391 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.955 |
guaA | tlr0100 | gene:10749038 | gene:10746678 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.499 |
guaA | tlr1272 | gene:10749038 | gene:10747868 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase; ORF_ID:tlr1272. | 0.900 |
guaA | tlr1281 | gene:10749038 | gene:10747877 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.582 |
guaA | tlr2338 | gene:10749038 | gene:10748957 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.995 |
purB | guaA | gene:10748434 | gene:10749038 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.875 |
purB | purH | gene:10748434 | gene:10748148 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | 0.995 |
purB | tll0771 | gene:10748434 | gene:10747362 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.900 |
purB | tll1786 | gene:10748434 | gene:10748391 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.925 |
purB | tlr0100 | gene:10748434 | gene:10746678 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.944 |
purB | tlr1272 | gene:10748434 | gene:10747868 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5'-nucleotidase; ORF_ID:tlr1272. | 0.900 |
purB | tlr2338 | gene:10748434 | gene:10748957 | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.961 |
purH | guaA | gene:10748148 | gene:10749038 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.853 |
purH | purB | gene:10748148 | gene:10748434 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | Adenylosuccinate lyase; ORF_ID:tll1829; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.995 |
purH | tll1786 | gene:10748148 | gene:10748391 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.927 |
purH | tlr1272 | gene:10748148 | gene:10747868 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | 5'-nucleotidase; ORF_ID:tlr1272. | 0.900 |
purH | tlr2338 | gene:10748148 | gene:10748957 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; ORF_ID:tlr1547; bifunctional. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.958 |