STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (530 aa)    
Predicted Functional Partners:
OKL43802.1
GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.952
OKL44646.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.947
gshB
Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
  
 
 0.859
OKL44983.1
Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
  
  0.765
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
  
    0.734
pepN
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.731
OKL42278.1
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.715
OKL44309.1
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.681
OKL44179.1
Leucyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M17 family.
     
 0.652
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.652
Your Current Organism:
Nesiotobacter exalbescens
NCBI taxonomy Id: 197461
Other names: ATCC BAA-994, CIP 108449, DSM 16456, N. exalbescens, Nesiotobacter exalbescens Donachie et al. 2006, Nesiotobacter sp. WB1-6, alpha proteobacterium LA33B, strain LA33B
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