| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKU11080.1 | AKU12066.1 | AzCIB_1175 | AzCIB_2171 | Para-aminobenzoate synthase, subunit I. | PARA-aminobenzoate synthetase component I protein. | 0.953 |
| AKU11080.1 | AKU13636.1 | AzCIB_1175 | AzCIB_3743 | Para-aminobenzoate synthase, subunit I. | Anthranilate synthase component II. | 0.999 |
| AKU11080.1 | AKU14255.1 | AzCIB_1175 | AzCIB_4362 | Para-aminobenzoate synthase, subunit I. | Threonine dehydratase. | 0.605 |
| AKU11080.1 | ilvA | AzCIB_1175 | AzCIB_4265 | Para-aminobenzoate synthase, subunit I. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.605 |
| AKU11080.1 | trpA | AzCIB_1175 | AzCIB_3035 | Para-aminobenzoate synthase, subunit I. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.972 |
| AKU11080.1 | trpB-2 | AzCIB_1175 | AzCIB_3036 | Para-aminobenzoate synthase, subunit I. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.969 |
| AKU11080.1 | trpC | AzCIB_1175 | AzCIB_3741 | Para-aminobenzoate synthase, subunit I. | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.994 |
| AKU11080.1 | trpD | AzCIB_1175 | AzCIB_3742 | Para-aminobenzoate synthase, subunit I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.989 |
| AKU11080.1 | trpE | AzCIB_1175 | AzCIB_3744 | Para-aminobenzoate synthase, subunit I. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.871 |
| AKU11080.1 | trpF | AzCIB_1175 | AzCIB_3037 | Para-aminobenzoate synthase, subunit I. | N-(5-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.970 |
| AKU12066.1 | AKU11080.1 | AzCIB_2171 | AzCIB_1175 | PARA-aminobenzoate synthetase component I protein. | Para-aminobenzoate synthase, subunit I. | 0.953 |
| AKU12066.1 | AKU13636.1 | AzCIB_2171 | AzCIB_3743 | PARA-aminobenzoate synthetase component I protein. | Anthranilate synthase component II. | 0.999 |
| AKU12066.1 | AKU14255.1 | AzCIB_2171 | AzCIB_4362 | PARA-aminobenzoate synthetase component I protein. | Threonine dehydratase. | 0.605 |
| AKU12066.1 | ilvA | AzCIB_2171 | AzCIB_4265 | PARA-aminobenzoate synthetase component I protein. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.605 |
| AKU12066.1 | trpA | AzCIB_2171 | AzCIB_3035 | PARA-aminobenzoate synthetase component I protein. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.968 |
| AKU12066.1 | trpB-2 | AzCIB_2171 | AzCIB_3036 | PARA-aminobenzoate synthetase component I protein. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.962 |
| AKU12066.1 | trpC | AzCIB_2171 | AzCIB_3741 | PARA-aminobenzoate synthetase component I protein. | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.993 |
| AKU12066.1 | trpD | AzCIB_2171 | AzCIB_3742 | PARA-aminobenzoate synthetase component I protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.988 |
| AKU12066.1 | trpE | AzCIB_2171 | AzCIB_3744 | PARA-aminobenzoate synthetase component I protein. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.874 |
| AKU12066.1 | trpF | AzCIB_2171 | AzCIB_3037 | PARA-aminobenzoate synthetase component I protein. | N-(5-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.966 |