STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyADNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (145 aa)    
Predicted Functional Partners:
expI
Homoserine lactone synthase YpeI; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone), an autoinducer molecule which binds to ExpR and thus acts in virulence (soft rot disease) through the activation of genes for plant tissue macerating enzymes.
  
   
 0.596
fis
Global DNA-binding transcriptional dual regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
      
 0.561
vfmE
VfmE belongs to the AraC family of transcriptional regulators; Protein involved in transcription factor activity, sequence-specific DNA binding, DNA binding, transcription, regulation of transcription, DNA-dependent, metabolism by symbiont of substance in host, regulation of transcription and pathogenesis.
  
  
 0.482
ydhL
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
       0.459
pecS
DNA-binding transcriptional regulatory protein PecS; Negative regulator of pectinase, cellulase, blue pigment production and virulence genes. Also binds to promoter sites in the pecS-pecM intergenic region and negatively autoregulate its expression as well as that of pecM.
  
   
 0.437
aaeA
P-hydroxybenzoic acid efflux pump subunit AaeA; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.430
pnp
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
      
 0.419
ihfA
Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
    0.416
ihfB
Integration host factor (IHF), DNA-binding protein, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
  
 0.406
lpp
Murein lipoprotein.
  
    0.405
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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