node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADM99925.1 | ADN00752.1 | Dda3937_03440 | Dda3937_01104 | FOG: TPR repeat; Protein involved in (DEPRECATED) molecular function unknown, binding and (DEPRECATED) biological process unknown. | High-affnity carbon uptake protein Hat/HatR; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.910 |
ADM99925.1 | alaS | Dda3937_03440 | Dda3937_03152 | FOG: TPR repeat; Protein involved in (DEPRECATED) molecular function unknown, binding and (DEPRECATED) biological process unknown. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.891 |
ADN00752.1 | ADM99925.1 | Dda3937_01104 | Dda3937_03440 | High-affnity carbon uptake protein Hat/HatR; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | FOG: TPR repeat; Protein involved in (DEPRECATED) molecular function unknown, binding and (DEPRECATED) biological process unknown. | 0.910 |
ADN00752.1 | alaS | Dda3937_01104 | Dda3937_03152 | High-affnity carbon uptake protein Hat/HatR; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.942 |
ADN00752.1 | sseB | Dda3937_01104 | Dda3937_03698 | High-affnity carbon uptake protein Hat/HatR; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | Rhodanase-like enzyme, sulfur transfer from thiosulfate; Protein involved in sulfur metabolic process. | 0.892 |
alaS | ADM99925.1 | Dda3937_03152 | Dda3937_03440 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | FOG: TPR repeat; Protein involved in (DEPRECATED) molecular function unknown, binding and (DEPRECATED) biological process unknown. | 0.891 |
alaS | ADN00752.1 | Dda3937_03152 | Dda3937_01104 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | High-affnity carbon uptake protein Hat/HatR; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.942 |
alaS | ileS | Dda3937_03152 | Dda3937_01396 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.772 |
alaS | leuS | Dda3937_03152 | Dda3937_02477 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; Protein involved in leucine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and leucyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.827 |
alaS | metG | Dda3937_03152 | Dda3937_03935 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.799 |
alaS | pheT | Dda3937_03152 | Dda3937_03678 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | Phenylalanine tRNA synthetase, beta subunit; Protein involved in tRNA binding, phenylalanine-tRNA ligase activity, ATP binding, tRNA aminoacylation for protein translation and phenylalanyl-tRNA aminoacylation; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.873 |
alaS | purL | Dda3937_03152 | Dda3937_03379 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.778 |
alaS | sseB | Dda3937_03152 | Dda3937_03698 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | Rhodanase-like enzyme, sulfur transfer from thiosulfate; Protein involved in sulfur metabolic process. | 0.891 |
alaS | thrS | Dda3937_03152 | Dda3937_03683 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.864 |
alaS | valS | Dda3937_03152 | Dda3937_01296 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.851 |
ileS | alaS | Dda3937_01396 | Dda3937_03152 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.772 |
ileS | leuS | Dda3937_01396 | Dda3937_02477 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | leucyl-tRNA synthetase; Protein involved in leucine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and leucyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.928 |
ileS | metG | Dda3937_01396 | Dda3937_03935 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.919 |
ileS | pheT | Dda3937_01396 | Dda3937_03678 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Phenylalanine tRNA synthetase, beta subunit; Protein involved in tRNA binding, phenylalanine-tRNA ligase activity, ATP binding, tRNA aminoacylation for protein translation and phenylalanyl-tRNA aminoacylation; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.965 |
ileS | purL | Dda3937_01396 | Dda3937_03379 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.692 |