node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisI | ribD1 | BUsg_099 | BUsg_445 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | Riboflavin biosynthesis protein RibD. | 0.464 |
hisI | ribD2 | BUsg_099 | BUsg_446 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | Riboflavin biosynthesis protein RibD; Belongs to the HTP reductase family. | 0.464 |
hisI | ribE | BUsg_099 | BUsg_104 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | Riboflavin synthase alpha chain; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.835 |
hisI | ribH | BUsg_099 | BUsg_443 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.401 |
hisI | rnfA | BUsg_099 | BUsg_105 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | Putative membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.420 |
hisI | rpmE | BUsg_099 | BUsg_556 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | 50S ribosomal protein L31; Binds the 23S rRNA. | 0.929 |
hisI | ydgM | BUsg_099 | BUsg_106 | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | Putative ferredoxin-like protein in add-nth; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.422 |
ribA | ribB | BUsg_261 | BUsg_056 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.926 |
ribA | ribD1 | BUsg_261 | BUsg_445 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | Riboflavin biosynthesis protein RibD. | 0.991 |
ribA | ribD2 | BUsg_261 | BUsg_446 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | Riboflavin biosynthesis protein RibD; Belongs to the HTP reductase family. | 0.916 |
ribA | ribE | BUsg_261 | BUsg_104 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | Riboflavin synthase alpha chain; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.996 |
ribA | ribH | BUsg_261 | BUsg_443 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.986 |
ribB | ribA | BUsg_056 | BUsg_261 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.926 |
ribB | ribD1 | BUsg_056 | BUsg_445 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin biosynthesis protein RibD. | 0.955 |
ribB | ribD2 | BUsg_056 | BUsg_446 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin biosynthesis protein RibD; Belongs to the HTP reductase family. | 0.955 |
ribB | ribE | BUsg_056 | BUsg_104 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase alpha chain; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.999 |
ribB | ribH | BUsg_056 | BUsg_443 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.999 |
ribD1 | hisI | BUsg_445 | BUsg_099 | Riboflavin biosynthesis protein RibD. | Histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the PRA-PH family. | 0.464 |
ribD1 | ribA | BUsg_445 | BUsg_261 | Riboflavin biosynthesis protein RibD. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.991 |
ribD1 | ribB | BUsg_445 | BUsg_056 | Riboflavin biosynthesis protein RibD. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.955 |