STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
araBL-ribulokinase; Escherichia coli K-12 ortholog: b0063; Escherichia coli O157:H7 ortholog: z0072. (566 aa)    
Predicted Functional Partners:
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
 
 
 0.999
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
 
 
 0.999
sgbE
Probable sugar isomerase sgbE; Escherichia coli K-12 ortholog: b3583; Escherichia coli O157:H7 ortholog: z0069.
 
 
 0.991
sgaE
Probable sugar isomerase sgaE; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization.
 
 
 0.990
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
  
  
 0.949
rhaB
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
  
  
 0.936
rpe
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
 
   
 0.905
sgbU
Putative hexulose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b3582; Escherichia coli O157:H7 ortholog: z5806.
    
  0.902
sgaU
Putative hexulose-6-phosphate isomerase; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family.
    
  0.902
araE
Arabinose-proton symporter; Arabinose transporter; Escherichia coli K-12 ortholog: b2841; Escherichia coli O157:H7 ortholog: z4161; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.881
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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