STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yabJThiamine transport ATP-binding protein thiQ; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (239 aa)    
Predicted Functional Partners:
yabK
Thiamine transport system permease protein thiP; Escherichia coli K-12 ortholog: b0067; Escherichia coli O157:H7 ortholog: z0076.
 
 
 0.999
tbpA
Thiamine-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b0068; Escherichia coli O157:H7 ortholog: z0077.
 
 
  0.988
yjgF
Protein yjgF; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis (By similarity); Belongs to the RutC family.
      
 0.682
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome (By similarity); Belongs to the universal ribosomal protein uS11 family.
  
     0.584
ybeW
Chaperone protein hscC; Hsc62; Escherichia coli K-12 ortholog: b0650; Escherichia coli O157:H7 ortholog: z0800; Belongs to the heat shock protein 70 family.
  
     0.580
modB
Molybdenum transport system permease protein modB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
      0.579
ybbL
Hypothetical ABC transporter ATP-binding protein ybbL; Escherichia coli K-12 ortholog: b0490; Escherichia coli O157:H7 ortholog: z0643.
 
    
0.571
mdlB
Multidrug resistance-like ATP-binding protein mdlB; Escherichia coli K-12 ortholog: b0449; Escherichia coli O157:H7 ortholog: z0559; Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
 
    
0.548
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
     0.547
yabN
Hypothetical protein yabN; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
     
 0.523
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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