node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroD | aroP | c2088 | c0131 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 0.425 |
aroP | aroD | c0131 | c2088 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.425 |
aroP | mtr | c0131 | c3914 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Tryptophan-specific transport protein; Tryptophan permease; Escherichia coli K-12 ortholog: b3161; Escherichia coli O157:H7 ortholog: z4522. | 0.818 |
aroP | mutH | c0131 | c3426 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.515 |
aroP | tnaB | c0131 | c4632 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Low affinity tryptophan permease; Escherichia coli K-12 ortholog: b3709; Escherichia coli O157:H7 ortholog: z5204. | 0.787 |
aroP | tyrB | c0131 | c5031 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Aromatic-amino-acid aminotransferase; Escherichia coli K-12 ortholog: b4054; Escherichia coli O157:H7 ortholog: z5652. | 0.534 |
aroP | tyrP | c0131 | c2323 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Tyrosine-specific transport protein; Tyrosine permease; Escherichia coli K-12 ortholog: b1907; Escherichia coli O157:H7 ortholog: z2963. | 0.818 |
aroP | tyrR | c0131 | c1795 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Transcriptional Regulatory protein tyrR; Escherichia coli K-12 ortholog: b1323; Escherichia coli O157:H7 ortholog: z2454. | 0.819 |
aroP | yeaY | c0131 | c2210 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Hypothetical lipoprotein yeaY precursor; Escherichia coli K-12 ortholog: b1806; Escherichia coli O157:H7 ortholog: z2849. | 0.487 |
aroP | ygeD | c0131 | c3430 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Hypothetical protein ygeD; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | 0.798 |
aroP | yicG | c0131 | c4470 | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | Hypothetical protein yicG; Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071. | 0.634 |
mtr | aroP | c3914 | c0131 | Tryptophan-specific transport protein; Tryptophan permease; Escherichia coli K-12 ortholog: b3161; Escherichia coli O157:H7 ortholog: z4522. | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 0.818 |
mtr | tyrR | c3914 | c1795 | Tryptophan-specific transport protein; Tryptophan permease; Escherichia coli K-12 ortholog: b3161; Escherichia coli O157:H7 ortholog: z4522. | Transcriptional Regulatory protein tyrR; Escherichia coli K-12 ortholog: b1323; Escherichia coli O157:H7 ortholog: z2454. | 0.681 |
mutH | aroP | c3426 | c0131 | DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 0.515 |
mutH | yeaY | c3426 | c2210 | DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | Hypothetical lipoprotein yeaY precursor; Escherichia coli K-12 ortholog: b1806; Escherichia coli O157:H7 ortholog: z2849. | 0.696 |
mutH | ygeD | c3426 | c3430 | DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | Hypothetical protein ygeD; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | 0.800 |
mutH | yicG | c3426 | c4470 | DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | Hypothetical protein yicG; Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071. | 0.758 |
tnaB | aroP | c4632 | c0131 | Low affinity tryptophan permease; Escherichia coli K-12 ortholog: b3709; Escherichia coli O157:H7 ortholog: z5204. | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 0.787 |
tyrB | aroP | c5031 | c0131 | Aromatic-amino-acid aminotransferase; Escherichia coli K-12 ortholog: b4054; Escherichia coli O157:H7 ortholog: z5652. | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. | 0.534 |
tyrB | tyrR | c5031 | c1795 | Aromatic-amino-acid aminotransferase; Escherichia coli K-12 ortholog: b4054; Escherichia coli O157:H7 ortholog: z5652. | Transcriptional Regulatory protein tyrR; Escherichia coli K-12 ortholog: b1323; Escherichia coli O157:H7 ortholog: z2454. | 0.696 |