STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroPAromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (456 aa)    
Predicted Functional Partners:
tyrR
Transcriptional Regulatory protein tyrR; Escherichia coli K-12 ortholog: b1323; Escherichia coli O157:H7 ortholog: z2454.
      
 0.819
tyrP
Tyrosine-specific transport protein; Tyrosine permease; Escherichia coli K-12 ortholog: b1907; Escherichia coli O157:H7 ortholog: z2963.
      
 0.818
mtr
Tryptophan-specific transport protein; Tryptophan permease; Escherichia coli K-12 ortholog: b3161; Escherichia coli O157:H7 ortholog: z4522.
      
 0.818
ygeD
Hypothetical protein ygeD; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
      
 0.798
tnaB
Low affinity tryptophan permease; Escherichia coli K-12 ortholog: b3709; Escherichia coli O157:H7 ortholog: z5204.
      
 0.787
yicG
Hypothetical protein yicG; Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071.
      
 0.634
tyrB
Aromatic-amino-acid aminotransferase; Escherichia coli K-12 ortholog: b4054; Escherichia coli O157:H7 ortholog: z5652.
   
  
 0.534
mutH
DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.
      
 0.515
yeaY
Hypothetical lipoprotein yeaY precursor; Escherichia coli K-12 ortholog: b1806; Escherichia coli O157:H7 ortholog: z2849.
      
 0.487
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
      
 0.425
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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