node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceE | c5032 | c0142 | c5032 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | 0.450 |
aceE | c5034 | c0142 | c5034 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | 0.830 |
aceE | lpdA | c0142 | c0145 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.994 |
aceE | sucA | c0142 | c0803 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.462 |
aceE | sucB | c0142 | c0804 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.832 |
aceE | ydbK | c0142 | c1823 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Probable pyruvate-flavodoxin oxidoreductase; Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332. | 0.968 |
c5032 | aceE | c5032 | c0142 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.450 |
c5032 | c5034 | c5032 | c5034 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | 0.999 |
c5032 | gcvH | c5032 | c3484 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.786 |
c5032 | gcvP | c5032 | c3483 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.719 |
c5032 | gcvT | c5032 | c3485 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.518 |
c5032 | lpdA | c5032 | c0145 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.975 |
c5032 | sucA | c5032 | c0803 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | 2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.905 |
c5032 | sucB | c5032 | c0804 | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
c5034 | aceE | c5034 | c0142 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.830 |
c5034 | c5032 | c5034 | c5032 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | 2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880. | 0.999 |
c5034 | gcvH | c5034 | c3484 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.843 |
c5034 | gcvP | c5034 | c3483 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.635 |
c5034 | gcvT | c5034 | c3485 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.543 |
c5034 | lpdA | c5034 | c0145 | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881. | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.995 |