STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacZBeta-galactosidase; Escherichia coli K-12 ortholog: b0344; Escherichia coli O157:H7 ortholog: z0440; Belongs to the glycosyl hydrolase 2 family. (1024 aa)    
Predicted Functional Partners:
lacY
Lactose-proton symport; Escherichia coli K-12 ortholog: b0343; Escherichia coli O157:H7 ortholog: z0439.
 
  
 0.992
lacA
Galactoside O-acetyltransferase; Escherichia coli K-12 ortholog: b0342; Escherichia coli O157:H7 ortholog: z0438.
 
  
 0.980
ebgC
Evolved beta-galactosidase beta-subunit; Required for full activity of the EbgA enzyme. Exact function not known (By similarity).
   
  0.930
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
 
 0.927
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.922
ebgA
Evolved beta-galactosidase alpha-subunit; Escherichia coli K-12 ortholog: b3076; Escherichia coli O157:H7 ortholog: z4429.
  
  
 
0.918
c0460
LacI protein; Residues 12 to 88 of 88 are 88.31 pct identical to residues 284 to 360 of 360 from GenPept.129 : >gb|AAL59004.1| (AY070365) Lac repressor [Expression vector pFHC2102].
     
 0.917
melA
Alpha-galactosidase; Escherichia coli K-12 ortholog: b4119; Escherichia coli O157:H7 ortholog: z5721.
 
  
 0.915
yphB
Hypothetical protein yphB; Escherichia coli K-12 ortholog: b2544; Escherichia coli O157:H7 ortholog: z3816.
  
 
 0.908
c4831
Hypothetical protein; Residues 46 to 310 of 314 are 43.39 pct identical to residues 4 to 259 of 262 from GenPept.129 : >emb|CAB42038.1| (AL049754) hypothetical protein [Streptomyces coelicolor A3(2)].
  
 
 0.908
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.