STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybaCAcetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. (319 aa)    
Predicted Functional Partners:
nuoC
NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
    
   0.691
caiB
Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily.
 
    0.630
gsk
Inosine-guanosine kinase; Escherichia coli K-12 ortholog: b0477; Escherichia coli O157:H7 ortholog: z0596; Belongs to the carbohydrate kinase PfkB family.
  
    0.541
caiC
Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine.
  
   0.515
yaaU
Hypothetical metabolite transport protein yaaU; Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051.
  
     0.508
caiA
Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family.
 
  
 0.473
ydiD
Hypothetical protein ydiD; Escherichia coli K-12 ortholog: b1701; Escherichia coli O157:H7 ortholog: z2730.
  
   0.467
c1175
Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum].
      
 0.455
malY
MalY protein; Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; Cystathionine beta-lyase; Maltose regulon modulator.
      
 0.455
c3407
Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli].
      
 0.455
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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