node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
c1175 | c3407 | c1175 | c3407 | Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]. | Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]. | 0.922 |
c1175 | malY | c1175 | c2014 | Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]. | MalY protein; Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; Cystathionine beta-lyase; Maltose regulon modulator. | 0.918 |
c1175 | ybaC | c1175 | c0596 | Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]. | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | 0.455 |
c3407 | c1175 | c3407 | c1175 | Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]. | Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]. | 0.922 |
c3407 | malY | c3407 | c2014 | Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]. | MalY protein; Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; Cystathionine beta-lyase; Maltose regulon modulator. | 0.910 |
c3407 | ybaC | c3407 | c0596 | Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]. | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | 0.455 |
caiA | caiB | c0048 | c0047 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | 0.973 |
caiA | caiC | c0048 | c0046 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.921 |
caiA | nuoC | c0048 | c2827 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.872 |
caiA | yaaU | c0048 | c0055 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical metabolite transport protein yaaU; Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051. | 0.423 |
caiA | ybaC | c0048 | c0596 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | 0.473 |
caiA | ydiD | c0048 | c2097 | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | Hypothetical protein ydiD; Escherichia coli K-12 ortholog: b1701; Escherichia coli O157:H7 ortholog: z2730. | 0.412 |
caiB | caiA | c0047 | c0048 | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.973 |
caiB | caiC | c0047 | c0046 | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | 0.974 |
caiB | yaaU | c0047 | c0055 | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Hypothetical metabolite transport protein yaaU; Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051. | 0.654 |
caiB | ybaC | c0047 | c0596 | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | 0.630 |
caiC | caiA | c0046 | c0048 | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Crotonobetainyl-CoA dehydrogenase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. | 0.921 |
caiC | caiB | c0046 | c0047 | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Crotonobetainyl-CoA:carnitine CoA-transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. | 0.974 |
caiC | yaaU | c0046 | c0055 | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Hypothetical metabolite transport protein yaaU; Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051. | 0.538 |
caiC | ybaC | c0046 | c0596 | Probable crotonobetaine/carnitine-CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | 0.515 |