STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybbUHTH-type transcriptional repressor AllR; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region (By similarity) (271 aa)    
Predicted Functional Partners:
gcl
Glyoxylate carboligase; Escherichia coli K-12 ortholog: b0507; Escherichia coli O157:H7 ortholog: z0661; Belongs to the TPP enzyme family
 
     0.873
gip
Hydroxypyruvate isomerase; Escherichia coli K-12 ortholog: b0508; Escherichia coli O157:H7 ortholog: z0662; Belongs to the hyi family
 
     0.858
ybbT
Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate
 
     0.670
ybbQ
2-hydroxy-3-oxopropionate reductase; Escherichia coli K-12 ortholog: b0509; Escherichia coli O157:H7 ortholog: z0663
       0.558
ybbW
Putative allantoin permease; Allantoin transport protein; Escherichia coli K-12 ortholog: b0511; Escherichia coli O157:H7 ortholog: z0665
 
     0.449
ybbX
Allantoinase; Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family
 
     0.445
uxuR
Uxu operon transcriptional regulator; Escherichia coli K-12 ortholog: b4324; Escherichia coli O157:H7 ortholog: z5922
  
 
 0.401
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: low (8%) [HD]