STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citG2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family. (292 aa)    
Predicted Functional Partners:
ybdU
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein; Belongs to the CitX family.
 
 0.999
citC
[Citrate [pro-3S]-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
  
 0.983
citE
Citrate lyase beta chain; Represents a citryl-ACP lyase; Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
 
  
 0.974
citF
Citrate lyase alpha chain; Escherichia coli K-12 ortholog: b0615; Escherichia coli O157:H7 ortholog: z0759.
 
  
 0.948
ybdS
Citrate carrier/transporter; Escherichia coli K-12 ortholog: b0612; Escherichia coli O157:H7 ortholog: z0756.
 
  
 0.833
c0703
Hypothetical protein.
       0.572
c5038
Putative membrane-bound protein; Residues 10 to 499 of 501 are 60.28 pct identical to residues 20 to 511 of 513 from SwissProt.40 : >sp|Q07252|MEMP_ALCEU MEMBRANE PROTEIN.
  
  
 0.509
rna
Ribonuclease I precursor; Escherichia coli K-12 ortholog: b0611; Escherichia coli O157:H7 ortholog: z0755; Belongs to the RNase T2 family.
       0.436
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.429
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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