node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cutC | ybhE | c2289 | c0844 | Putative conserved protein; Participates in the control of copper homeostasis. | Hypothetical protein ybhE; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.515 |
edd | gnd | c2264 | c2556 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.967 |
edd | gntK | c2264 | c4225 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | 0.945 |
edd | idnK | c2264 | c5369 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Thermosensitive gluconokinase; Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805. | 0.936 |
edd | ybhE | c2264 | c0844 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Hypothetical protein ybhE; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.906 |
edd | zwf | c2264 | c2265 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.984 |
fruB | uxuA | c2704 | c5402 | PTS system, fructose-specific IIA/FPr component; EIIA-Fru; Escherichia coli K-12 ortholog: b2169; Escherichia coli O157:H7 ortholog: z3427. | Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. | 0.493 |
fruB | ybhE | c2704 | c0844 | PTS system, fructose-specific IIA/FPr component; EIIA-Fru; Escherichia coli K-12 ortholog: b2169; Escherichia coli O157:H7 ortholog: z3427. | Hypothetical protein ybhE; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.520 |
gnd | edd | c2556 | c2264 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.967 |
gnd | gntK | c2556 | c4225 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | 0.993 |
gnd | idnK | c2556 | c5369 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Thermosensitive gluconokinase; Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805. | 0.993 |
gnd | uxuA | c2556 | c5402 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. | 0.800 |
gnd | ybhE | c2556 | c0844 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Hypothetical protein ybhE; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.938 |
gnd | zwf | c2556 | c2265 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.997 |
gntK | edd | c4225 | c2264 | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.945 |
gntK | gnd | c4225 | c2556 | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.993 |
gntK | idnK | c4225 | c5369 | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | Thermosensitive gluconokinase; Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805. | 0.905 |
gntK | ybhE | c4225 | c0844 | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | Hypothetical protein ybhE; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.900 |
gntK | zwf | c4225 | c2265 | Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.406 |
idnK | edd | c5369 | c2264 | Thermosensitive gluconokinase; Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.936 |