STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
focA_2Probable formate transporter 1; Involved in the bidirectional transport of formate. Belongs to the FNT transporter (TC 2.A.44) family. (398 aa)    
Predicted Functional Partners:
tdcE
Keto-acid formate acetyltransferase; Escherichia coli K-12 ortholog: b3114; Escherichia coli O157:H7 ortholog: z4466.
 
  
 0.730
fdhF
Formate dehydrogenase H; Escherichia coli K-12 ortholog: b4079; Escherichia coli O157:H7 ortholog: z5678; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.717
fhlA
Formate hydrogenlyase transcriptional activator; Escherichia coli K-12 ortholog: b2731; Escherichia coli O157:H7 ortholog: z4040.
      
 0.681
yadF
Protein yadF; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
    0.658
ycaO
Hypothetical protein ycaO; Escherichia coli K-12 ortholog: b0905; Escherichia coli O157:H7 ortholog: z1251.
     
 0.623
nirD
Nitrite reductase [NAD(P)H] small subunit; Escherichia coli K-12 ortholog: b3366; Escherichia coli O157:H7 ortholog: z4727.
 
  
 0.499
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.486
gltB
Glutamate synthase [NADPH] large chain precursor; Escherichia coli K-12 ortholog: b3212; Escherichia coli O157:H7 ortholog: z4576.
   
  
 0.448
adhE
Aldehyde-alcohol dehydrogenase; Escherichia coli K-12 ortholog: b1241; Escherichia coli O157:H7 ortholog: z2016; multifunctional; Alcohol dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; Pyruvate-formate-lyase deactivase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.441
ycaP
Hypothetical protein ycaP; Escherichia coli K-12 ortholog: b0906; Escherichia coli O157:H7 ortholog: z1252.
  
    0.428
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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