node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frr | guaA | c0208 | c3026 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.717 |
frr | prfA | c0208 | c1669 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.984 |
frr | prfB | c0208 | c5622 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.975 |
frr | pth | c0208 | c1662 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.716 |
frr | rpmA | c0208 | c3942 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L27; Escherichia coli K-12 ortholog: b3185; Escherichia coli O157:H7 ortholog: z4547; Belongs to the bacterial ribosomal protein bL27 family. | 0.965 |
frr | yaeJ | c0208 | c0230 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Hypothetical protein yaeJ; Escherichia coli K-12 ortholog: b0191; Escherichia coli O157:H7 ortholog: z0203. | 0.771 |
guaA | frr | c3026 | c0208 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.717 |
guaA | pth | c3026 | c1662 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.769 |
guaA | rpmA | c3026 | c3942 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L27; Escherichia coli K-12 ortholog: b3185; Escherichia coli O157:H7 ortholog: z4547; Belongs to the bacterial ribosomal protein bL27 family. | 0.584 |
guaA | ychF | c3026 | c1661 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Probable GTP-binding protein ychF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.789 |
lytB | pth | c0033 | c1662 | IspH protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.744 |
mfd | prfB | c1389 | c5622 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; Belongs to the UvrB family. In the N-terminal section; belongs to the UvrB family. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.603 |
mfd | pth | c1389 | c1662 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; Belongs to the UvrB family. In the N-terminal section; belongs to the UvrB family. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.663 |
mfd | yaeJ | c1389 | c0230 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; Belongs to the UvrB family. In the N-terminal section; belongs to the UvrB family. | Hypothetical protein yaeJ; Escherichia coli K-12 ortholog: b0191; Escherichia coli O157:H7 ortholog: z0203. | 0.539 |
phrB | pth | c0787 | c1662 | Deoxyribodipyrimidine photolyase; Escherichia coli K-12 ortholog: b0708; Escherichia coli O157:H7 ortholog: z0859; Belongs to the DNA photolyase family. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.905 |
prfA | frr | c1669 | c0208 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.984 |
prfA | prfB | c1669 | c5622 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.652 |
prfA | pth | c1669 | c1662 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.765 |
prfA | rpmA | c1669 | c3942 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 50S ribosomal protein L27; Escherichia coli K-12 ortholog: b3185; Escherichia coli O157:H7 ortholog: z4547; Belongs to the bacterial ribosomal protein bL27 family. | 0.942 |
prfA | yaeJ | c1669 | c0230 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Hypothetical protein yaeJ; Escherichia coli K-12 ortholog: b0191; Escherichia coli O157:H7 ortholog: z0203. | 0.832 |