STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yddMHypothetical protein yddM; Escherichia coli K-12 ortholog: b1477; Escherichia coli O157:H7 ortholog: z2233; Belongs to the VapA/VapI family. (94 aa)    
Predicted Functional Partners:
c1910
Hypothetical protein; Residues 2 to 90 of 90 are 56.17 pct identical to residues 4 to 92 of 92 from GenPept.129 : >gb|AAC43982.1| (U43847) killer protein [Plasmid Rts1].
 
 
 
 0.981
higA
Hypothetical protein ygjM; Antitoxin component of a type II toxin-antitoxin (TA) system. Functions as an mRNA interferase antitoxin.
  
   
 0.730
higB
Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. A probable translation-dependent mRNA interferase. Probably counteracted by antitoxin HigA.
 
   
 0.606
hipB
Protein hipB; Antitoxin component of a type II type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA. Represses the hipBA operon promoter (By similarity).
      
 0.511
abrB
AbrB protein; AidB regulator; Escherichia coli K-12 ortholog: b0715; Escherichia coli O157:H7 ortholog: z0867.
      
 0.505
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.
      
 0.491
adhP
Alcohol dehydrogenase, propanol-preferring; Escherichia coli K-12 ortholog: b1478; Escherichia coli O157:H7 ortholog: z2232.
  
  
 0.482
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.