STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhDProtein ydhD; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. (115 aa)    
Predicted Functional Partners:
bolA
BolA protein; Transcriptional regulator that plays an important role in general stress response.
 
 
 0.976
grxC
Glutaredoxin 3; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity); Belongs to the glutaredoxin family.
 
 
 0.937
yrbA
Protein yrbA; Involved in cell resistance against acid stress.
 
 
 
 0.918
yhgI
Protein yhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.876
grxA
Grx1; Escherichia coli K-12 ortholog: b0849; Escherichia coli O157:H7 ortholog: z1076.
 
 
 0.863
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase; Escherichia coli K-12 ortholog: b2907; Escherichia coli O157:H7 ortholog: z4244.
  
    0.697
yleB
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Escherichia coli K-12 ortholog: b0662; Escherichia coli O157:H7 ortholog: z0811.
  
    0.618
gshB
Glutathione synthetase; Escherichia coli K-12 ortholog: b2947; Escherichia coli O157:H7 ortholog: z4292.
  
     0.617
ydiC
SufA protein; Escherichia coli K-12 ortholog: b1684; Escherichia coli O157:H7 ortholog: z2712; Belongs to the HesB/IscA family.
 
 0.608
yadR
Hypothetical protein yadR; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.600
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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