STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ydjCHypothetical protein ydjC; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6 [...] (252 aa)    
Predicted Functional Partners:
celF
6-phospho-beta-glucosidase; Escherichia coli K-12 ortholog: b1734; Escherichia coli O157:H7 ortholog: z2764.
 
 
 0.993
celD
Cel operon repressor; Escherichia coli K-12 ortholog: b1735; Escherichia coli O157:H7 ortholog: z2765.
 
   
 0.968
celB
PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
   
 0.957
celA
PTS system, cellobiose-specific IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2).
 
   
 0.933
celC
PTS system, cellobiose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2).
 
   
 0.881
c1957
PTS system, cellobiose-specific IIA component; EIIA-Cel; Escherichia coli K-12 ortholog: b1736; Escherichia coli O157:H7 ortholog: z2766.
 
   
 0.501
yfbI
Hypothetical protein yfbI; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
 
  
 0.478
c1958
Putative conserved protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
   
 0.451
c1959
PTS system, cellobiose-specific IIB component; EIIB-Cel; Escherichia coli K-12 ortholog: b1738; Escherichia coli O157:H7 ortholog: z2768.
 
   
 0.450
yhjM
Endoglucanase precursor; Escherichia coli K-12 ortholog: b3531; Escherichia coli O157:H7 ortholog: z4946; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
   
 0.411
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.