STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gatDGalactitol-1-phosphate 5-dehydrogenase; Escherichia coli K-12 ortholog: b2091; Escherichia coli O157:H7 ortholog: z3254. (346 aa)    
Predicted Functional Partners:
gatB
PTS system, galactitol-specific IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport.
 
 
 0.999
gatA
PTS system, galactitol-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport.
 
 
 0.999
gatZ
Putative tagatose 6-phosphate kinase gatZ; Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.
  
  
 0.989
gatC
PTS system, galactitol-specific IIC component; EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z3255.
 
 
 0.983
c4279
PTS system, galactitol-specific IIC component; EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z4877.
 
  0.937
c4278
Putative phosphotransferase system enzyme subunit; Escherichia coli O157:H7 ortholog: z4876.
 
 
  0.929
c4277
Putative phosphotransferase system enzyme subunit; Escherichia coli O157:H7 ortholog: z4875.
  
 
  0.928
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 
 0.908
agaI
Putative galactosamine-6-phosphate isomerase; Escherichia coli K-12 ortholog: b3141; Escherichia coli O157:H7 ortholog: z4497.
   
 
 0.904
pfkB
6-phosphofructokinase isozyme 2; Escherichia coli K-12 ortholog: b1723; Escherichia coli O157:H7 ortholog: z2752; Belongs to the carbohydrate kinase PfkB family.
    
  0.902
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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