STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcEHypothetical protein yfcE; Shows phosphodiesterase activity; Belongs to the metallophosphoesterase superfamily. YfcE family. (184 aa)    
Predicted Functional Partners:
yggV
HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.756
yfcD
Hypothetical protein yfcD; Escherichia coli K-12 ortholog: b2299; Escherichia coli O157:H7 ortholog: z3561.
  
    0.709
yfcF
Hypothetical GST-like protein yfcF; Escherichia coli K-12 ortholog: b2301; Escherichia coli O157:H7 ortholog: z3563.
       0.633
yahD
Hypothetical ANK-repeats protein yahD; Escherichia coli K-12 ortholog: b0318; Escherichia coli O157:H7 ortholog: z0407.
    
 
 0.630
ycdZ
Hypothetical protein ycdZ; Escherichia coli K-12 ortholog: b1036; Escherichia coli O157:H7 ortholog: z1669.
  
     0.541
ycdX
Hypothetical protein ycdX precursor; Escherichia coli K-12 ortholog: b1034; Escherichia coli O157:H7 ortholog: z1667; Belongs to the PHP family.
 
    0.440
yfcG
Hypothetical GST-like protein yccG; Escherichia coli K-12 ortholog: b2302; Escherichia coli O157:H7 ortholog: z3564; Belongs to the GST superfamily.
       0.435
folX
D-erythro-7,8-dihydroneopterin triphosphate epimerase; Catalyzes the epimerization of carbon 2' of the side chain of 7,8-dihydroneopterin triphosphate (H2NTP) to form 7,8-dihydromonapterin triphosphate (H2MTP). Is required for tetrahydromonapterin biosynthesis.
  
    0.417
yfcH
Hypothetical protein yfcH; Escherichia coli K-12 ortholog: b2304; Escherichia coli O157:H7 ortholog: z3566.
       0.414
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.