STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ptsHPhosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (85 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate-protein phosphotransferase; Escherichia coli K-12 ortholog: b2416; Escherichia coli O157:H7 ortholog: z3682.
 
 0.999
crr
PTS system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
 
 0.999
c5406
Hypothetical protein; Residues 1 to 113 of 113 are 95.57 pct identical to residues 424 to 536 of 536 from GenPept.129 : >gb|AAL61895.1| (AF289032) putative phosphoenolpyruvate-protein phosphoryltransferase PptE [Escherichia coli].
 
 
 0.992
ptsG
PTS system, glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration.
  
 
 0.991
fruA
PTS system, fructose-specific IIBC component; EIIBC-Fru; Escherichia coli K-12 ortholog: b2167; Escherichia coli O157:H7 ortholog: z3425.
  
 
 0.991
mtlA
PTS system, mannitol-specific IIABC component; EIIABC-MTL; Escherichia coli K-12 ortholog: b3599; Escherichia coli O157:H7 ortholog: z5023.
 
 
 0.990
manX
PTS system, mannose-specific IIAB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA.
  
 0.986
c4758
PTS system, glucose-specific IIBC component; EIIBC-Glc; Escherichia coli K-12 ortholog: b1101; Escherichia coli O157:H7 ortholog: z1740.
  
 0.976
nagE
PTS system, N-acetylglucosamine-specific IIABC component; EIIABC-NAG; Escherichia coli K-12 ortholog: b0679; Escherichia coli O157:H7 ortholog: z0826.
 
 0.967
bglF
PTS system, beta-glucoside-specific IIABC component; EIIABC-Bgl; Escherichia coli K-12 ortholog: b3722.
  
 0.962
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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