node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
c5030 | cobB | c5030 | c1395 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.946 |
c5030 | mazG | c5030 | c3346 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | MazG protein; Escherichia coli K-12 ortholog: b2781; Escherichia coli O157:H7 ortholog: z4096. | 0.900 |
c5030 | nadE | c5030 | c2139 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.910 |
c5030 | nadR | c5030 | c5475 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | Transcriptional regulator nadR; Escherichia coli K-12 ortholog: b4390; Escherichia coli O157:H7 ortholog: z5991. | 0.931 |
c5030 | pntA | c5030 | c1995 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. | 0.900 |
c5030 | pntB | c5030 | c1994 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
c5030 | udhA | c5030 | c4923 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation. | 0.900 |
c5030 | ybeN | c5030 | c0730 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.910 |
c5030 | yfjB | c5030 | c3137 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.907 |
c5030 | yjaD | c5030 | c4953 | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | NADH pyrophosphatase; Escherichia coli K-12 ortholog: b3996; Escherichia coli O157:H7 ortholog: z5571. | 0.900 |
cobB | c5030 | c1395 | c5030 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]. | 0.946 |
cobB | mazG | c1395 | c3346 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | MazG protein; Escherichia coli K-12 ortholog: b2781; Escherichia coli O157:H7 ortholog: z4096. | 0.901 |
cobB | nadE | c1395 | c2139 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.926 |
cobB | nadR | c1395 | c5475 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Transcriptional regulator nadR; Escherichia coli K-12 ortholog: b4390; Escherichia coli O157:H7 ortholog: z5991. | 0.991 |
cobB | pntA | c1395 | c1995 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. | 0.909 |
cobB | pntB | c1395 | c1994 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
cobB | udhA | c1395 | c4923 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation. | 0.911 |
cobB | ybeN | c1395 | c0730 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.926 |
cobB | yfjB | c1395 | c3137 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.922 |
cobB | yjaD | c1395 | c4953 | CobB protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NADH pyrophosphatase; Escherichia coli K-12 ortholog: b3996; Escherichia coli O157:H7 ortholog: z5571. | 0.904 |