STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase; Escherichia coli K-12 ortholog: b2688; Escherichia coli O157:H7 ortholog: z3989; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (518 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Escherichia coli K-12 ortholog: b2947; Escherichia coli O157:H7 ortholog: z4292.
 
 
 0.986
pepN
Aminopeptidase N; Escherichia coli K-12 ortholog: b0932; Escherichia coli O157:H7 ortholog: z1280.
     
 0.939
ybdK
Hypothetical protein ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
     
 0.915
ggt
Gamma-glutamyltranspeptidase precursor; Escherichia coli K-12 ortholog: b3447; Escherichia coli O157:H7 ortholog: z4813.
    
  0.912
pepD
Aminoacyl-histidine dipeptidase; Escherichia coli K-12 ortholog: b0237; Escherichia coli O157:H7 ortholog: z0298.
   
 
 0.911
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Required for plasmid ColE1 site-specific recombination but not in its aminopeptidase activity. Could act as a structural component of the putative nucleoprotein complex in which the Xer recombination reaction takes place (By similarity); Belongs to the peptidase M17 family.
     
 0.907
pepB
Peptidase B; Probably plays an important role in intracellular peptide degradation.
     
 0.906
ybgJ
Hypothetical protein ybgJ; Escherichia coli K-12 ortholog: b0711; Escherichia coli O157:H7 ortholog: z0862.
     
  0.900
ybgK
Hypothetical protein ybgK; Escherichia coli K-12 ortholog: b0712; Escherichia coli O157:H7 ortholog: z0863.
     
  0.900
ybgL
Protein ybgL; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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