STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygfOPutative purine permease ygfO; Specific, proton motive force-dependent high-affinity transporter for xanthine; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. (485 aa)    
Predicted Functional Partners:
c3462
Hypothetical protein yjcD; Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z4223.
 
  
 0.955
ybbY
Putative purine permease ybbY; Escherichia coli K-12 ortholog: b0513; Escherichia coli O157:H7 ortholog: z0668.
  
   
 0.877
ygfP
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
    0.869
yicO
Hypothetical protein yicO; Escherichia coli K-12 ortholog: b3664; Escherichia coli O157:H7 ortholog: z5209.
 
  
 0.786
yieG
Hypothetical protein yieG; Escherichia coli K-12 ortholog: b3714; Escherichia coli O157:H7 ortholog: z5209.
 
  
 0.786
c3459
Possible hypoxanthine oxidase xdhD; Escherichia coli K-12 ortholog: b2881; Escherichia coli O157:H7 ortholog: z4220.
 
  
 0.767
ygfK
Hypothetical protein ygfK; Escherichia coli K-12 ortholog: b2878; Escherichia coli O157:H7 ortholog: z4217.
 
  
 0.745
c5056
Hypothetical protein yjcD; Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z5663.
 
  
 0.727
ygfM
Hypothetical protein ygfM; Escherichia coli K-12 ortholog: b2880; Escherichia coli O157:H7 ortholog: z4219.
 
  
 0.702
pyrB
Aspartate carbamoyltransferase catalytic chain; Escherichia coli K-12 ortholog: b4245; Escherichia coli O157:H7 ortholog: z5856; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.623
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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