STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speBAgmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa)    
Predicted Functional Partners:
speC
Ornithine decarboxylase, constitutive; Escherichia coli K-12 ortholog: b2965; Escherichia coli O157:H7 ortholog: z4310.
    
 0.981
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.978
speF
Ornithine decarboxylase, inducible; Escherichia coli K-12 ortholog: b0693; Escherichia coli O157:H7 ortholog: z0839.
    
 0.967
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
 
 
 0.963
ygjG
Probable ornithine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 0.938
c4501
Putative conserved protein; Residues 7 to 750 of 789 are 38.82 pct identical to residues 4 to 744 of 756 from MG1655 : b4117.
    
 0.909
adiA
Biodegradative arginine decarboxylase; Escherichia coli K-12 ortholog: b4117; Escherichia coli O157:H7 ortholog: z5719.
    
 0.909
speG
Spermidine N(1)-acetyltransferase; Escherichia coli K-12 ortholog: b1584; Escherichia coli O157:H7 ortholog: z2571.
     
 0.906
putA
PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.786
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
     
 0.722
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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