node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
c3406 | kdsA | c3406 | c1674 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | 0.984 |
c3406 | kdsB | c3406 | c1059 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.809 |
c3406 | kdsB-2 | c3406 | c3689 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.792 |
c3406 | kdsD | c3406 | c3957 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | Hypothetical protein yrbH; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). | 0.913 |
c3406 | kdtA | c3406 | c4457 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of two 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. | 0.761 |
c3406 | kpsF | c3406 | c3686 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | Hypothetical protein yrbH; Involved in the biosynthesis of K-antigen capsules. Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Belongs to the SIS family. GutQ/KpsF subfamily. | 0.913 |
c3406 | lpxA | c3406 | c0218 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.699 |
c3406 | yrbI | c3406 | c3958 | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | Hypothetical protein yrbI; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.890 |
kdsA | c3406 | c1674 | c3406 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 0.984 |
kdsA | kdsB | c1674 | c1059 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.960 |
kdsA | kdsB-2 | c1674 | c3689 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.818 |
kdsA | kdsD | c1674 | c3957 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | Hypothetical protein yrbH; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). | 0.989 |
kdsA | kdtA | c1674 | c4457 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of two 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. | 0.920 |
kdsA | kpsF | c1674 | c3686 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | Hypothetical protein yrbH; Involved in the biosynthesis of K-antigen capsules. Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Belongs to the SIS family. GutQ/KpsF subfamily. | 0.979 |
kdsA | lpxA | c1674 | c0218 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.852 |
kdsA | yrbI | c1674 | c3958 | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | Hypothetical protein yrbI; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.994 |
kdsB | c3406 | c1059 | c3406 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Phosphosugar isomerase; Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546. | 0.809 |
kdsB | kdsA | c1059 | c1674 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 2-dehydro-3-deoxyphosphooctonate aldolase; Escherichia coli K-12 ortholog: b1215; Escherichia coli O157:H7 ortholog: z1986; Belongs to the KdsA family. | 0.960 |
kdsB | kdsB-2 | c1059 | c3689 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.911 |
kdsB | kdsD | c1059 | c3957 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Hypothetical protein yrbH; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). | 0.871 |