Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glcB | glcC | c3705 | c3710 | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | 0.717 |
| glcB | glcD | c3705 | c3709 | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.967 |
| glcB | glcG | c3705 | c3706 | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | 0.996 |
| glcB | yghK | c3705 | c3704 | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Glycolate permease glcA; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.614 |
| glcC | glcB | c3710 | c3705 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.717 |
| glcC | glcD | c3710 | c3709 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.828 |
| glcC | glcG | c3710 | c3706 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | 0.805 |
| glcC | nadR | c3710 | c5475 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Transcriptional regulator nadR; Escherichia coli K-12 ortholog: b4390; Escherichia coli O157:H7 ortholog: z5991. | 0.456 |
| glcC | udhA | c3710 | c4923 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation. | 0.496 |
| glcC | ydfH | c3710 | c1966 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Hypothetical transcriptional regulator ydfH; Escherichia coli K-12 ortholog: b1540; Escherichia coli O157:H7 ortholog: z2157. | 0.405 |
| glcC | ygaE | c3710 | c3212 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Hypothetical transcriptional regulator ygaE; Escherichia coli K-12 ortholog: b2664; Escherichia coli O157:H7 ortholog: z3963. | 0.440 |
| glcC | yghK | c3710 | c3704 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Glycolate permease glcA; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.571 |
| glcC | yigI | c3710 | c4741 | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | Hypothetical protein yigI; Escherichia coli K-12 ortholog: b3820; Escherichia coli O157:H7 ortholog: z5341. | 0.461 |
| glcD | glcB | c3709 | c3705 | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.967 |
| glcD | glcC | c3709 | c3710 | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | 0.828 |
| glcD | glcG | c3709 | c3706 | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | 0.825 |
| glcD | yghK | c3709 | c3704 | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Glycolate permease glcA; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.757 |
| glcG | glcB | c3706 | c3705 | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.996 |
| glcG | glcC | c3706 | c3710 | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | Glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector. | 0.805 |
| glcG | glcD | c3706 | c3709 | Protein glcG; Escherichia coli K-12 ortholog: b2977; Belongs to the GlcG family. | Glycolate oxidase subunit glcD; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)- lactate) with a similar rate. Does not link directly to O(2), and 2,6- dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.825 |
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