mdaB protein (Escherichia coli CFT073) - STRING interaction network

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Score

mdaB

Modulator of drug activity B; NADPH-specific quinone reductase. (193 aa)

Predicted Functional Partners:

ygiN

0.795

kefC

0.790

kefB

0.789

mdaA

0.694

acpD

0.690

yieF

0.622

ybdL

0.587

alaA

0.587

yabF

0.555

c3767

0.534

Your Current Organism:

Escherichia coli CFT073

NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acpD	mdaA	c1839	c0984	Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.	Oxygen-insensitive NADPH nitroreductase; Escherichia coli K-12 ortholog: b0851; Escherichia coli O157:H7 ortholog: z1078; Belongs to the flavin oxidoreductase frp family.	0.682
acpD	mdaB	c1839	c3768	Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.690
acpD	yieF	c1839	c4636	Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.	Hypothetical protein yieF; Escherichia coli K-12 ortholog: b3713; Escherichia coli O157:H7 ortholog: z5208.	0.683
alaA	mdaB	c2831	c3768	Probable aminotransferase yfbQ; Involved in the biosynthesis of alanine.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.587
c3767	mdaB	c3767	c3768	Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z0248.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.534
c3767	ygiN	c3767	c3769	Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z0248.	Protein ygiN; Escherichia coli K-12 ortholog: b3029; Escherichia coli O157:H7 ortholog: z4380.	0.403
kefB	kefC	c4125	c0057	Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	0.491
kefB	mdaB	c4125	c3768	Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.789
kefB	yabF	c4125	c0056	Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Putative NAD(P)H oxidoreductase yabF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.	0.957
kefC	kefB	c0057	c4125	Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	0.491
kefC	mdaB	c0057	c3768	Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.790
kefC	yabF	c0057	c0056	Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	Putative NAD(P)H oxidoreductase yabF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.	0.998
mdaA	acpD	c0984	c1839	Oxygen-insensitive NADPH nitroreductase; Escherichia coli K-12 ortholog: b0851; Escherichia coli O157:H7 ortholog: z1078; Belongs to the flavin oxidoreductase frp family.	Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.	0.682
mdaA	mdaB	c0984	c3768	Oxygen-insensitive NADPH nitroreductase; Escherichia coli K-12 ortholog: b0851; Escherichia coli O157:H7 ortholog: z1078; Belongs to the flavin oxidoreductase frp family.	Modulator of drug activity B; NADPH-specific quinone reductase.	0.694
mdaA	yieF	c0984	c4636	Oxygen-insensitive NADPH nitroreductase; Escherichia coli K-12 ortholog: b0851; Escherichia coli O157:H7 ortholog: z1078; Belongs to the flavin oxidoreductase frp family.	Hypothetical protein yieF; Escherichia coli K-12 ortholog: b3713; Escherichia coli O157:H7 ortholog: z5208.	0.822
mdaB	acpD	c3768	c1839	Modulator of drug activity B; NADPH-specific quinone reductase.	Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.	0.690
mdaB	alaA	c3768	c2831	Modulator of drug activity B; NADPH-specific quinone reductase.	Probable aminotransferase yfbQ; Involved in the biosynthesis of alanine.	0.587
mdaB	c3767	c3768	c3767	Modulator of drug activity B; NADPH-specific quinone reductase.	Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z0248.	0.534
mdaB	kefB	c3768	c4125	Modulator of drug activity B; NADPH-specific quinone reductase.	Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	0.789
mdaB	kefC	c3768	c0057	Modulator of drug activity B; NADPH-specific quinone reductase.	Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.	0.790