STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGArgininosuccinate synthase; Escherichia coli K-12 ortholog: b3172; Escherichia coli O157:H7 ortholog: z4534; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (447 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
  
 0.999
argH
Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518.
 
 
 0.999
argE
Acetylornithine deacetylase; Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.
  
 0.998
argA
Amino-acid acetyltransferase; Escherichia coli K-12 ortholog: b2818; Escherichia coli O157:H7 ortholog: z4135; Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.990
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.987
arcB-2
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.986
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.986
carB
Carbamoyl-phosphate synthase large chain; Escherichia coli K-12 ortholog: b0033; Escherichia coli O157:H7 ortholog: z0038.
 
 
 0.977
arcA-2
Putative arginine deiminase; Residues 7 to 407 of 407 are 47.79 pct identical to residues 10 to 416 of 418 from SwissProt.40 : >sp|P13981|ARCA_PSEAE Arginine deiminase (ADI) (Arginine dihydrolase) (AD).
     
 0.961
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.929
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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