STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikENickel transport ATP-binding protein nikE; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa)    
Predicted Functional Partners:
nikA
Nickel-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b3476; Escherichia coli O157:H7 ortholog: z4868.
 
 
 0.999
nikB
Nickel transport system permease protein nikB; Escherichia coli K-12 ortholog: b3477; Escherichia coli O157:H7 ortholog: z4869.
 
 0.999
nikC
Nickel transport system permease protein nikC; Escherichia coli K-12 ortholog: b3478; Escherichia coli O157:H7 ortholog: z4870.
 
 0.999
nikD
Nickel transport ATP-binding protein nikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
 
0.998
yddQ
Hypothetical ABC transporter permease protein yddQ; Escherichia coli K-12 ortholog: b1485; Escherichia coli O157:H7 ortholog: z2225.
  
 0.904
dppC
Dipeptide transport system permease protein dppC; Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
  
 0.877
yliD
Hypothetical ABC transporter permease protein yliD; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane.
  
 0.859
yhhG
Nickel responsive regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel (By similarity).
 
   
 0.852
oppC
Oligopeptide transport system permease protein oppC; Escherichia coli K-12 ortholog: b1245; Escherichia coli O157:H7 ortholog: z2021.
  
 0.791
yliC
Hypothetical ABC transporter permease protein yliC; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane.
  
 0.704
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.