STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdoHFormate dehydrogenase-O beta subunit; Allows to use formate as major electron donor during aerobic respiration. The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit (By similarity). (300 aa)    
Predicted Functional Partners:
fdoI
Formate dehydrogenase; Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase (By similarity).
 
 0.999
fdoG
Formate dehydrogenase-O, major subunit; Escherichia coli K-12 ortholog: b3894; Escherichia coli O157:H7 ortholog: z5436.
 
 0.999
fdnI
Formate dehydrogenase-N gamma subunit; Nitrate-inducible; Cytochrome b556 (FDN) subunit; Escherichia coli K-12 ortholog: b1476; Escherichia coli O157:H7 ortholog: z2234.
 
 
 0.971
fdnG
Formate dehydrogenase, nitrate-inducible, major subunit; Escherichia coli K-12 ortholog: b1474; Escherichia coli O157:H7 ortholog: z2236.
 
 
 0.965
fdhE
Protein fdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.957
yaiM
Hypothetical protein yaiM; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
     
  0.900
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.900
yeiG
Hypothetical protein yeiG; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
     
  0.900
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.811
c2988
NADP-dependent malic enzyme; Escherichia coli K-12 ortholog: b2463; Escherichia coli O157:H7 ortholog: z3719.
    
 0.805
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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