STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate (489 aa)    
Predicted Functional Partners:
rhaA
L-rhamnose isomerase; Escherichia coli K-12 ortholog: b3903; Escherichia coli O157:H7 ortholog: z5447
 
 0.999
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde; Belongs to the aldolase class II family. RhaD subfamily
 
 
 0.995
lyxK
Cryptic L-xylulose kinase; Escherichia coli K-12 ortholog: b3580; Belongs to the FGGY kinase family
   
 
0.904
rhaR
HTH-type transcriptional activator RhaR; Activates expression of the rhaSR operon in response to L-rhamnose
 
  
 0.904
yiiL
L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose
 
   
 0.900
rhaT
L-rhamnose-proton symporter; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system)
 
  
 0.888
rhaS
HTH-type transcriptional activator RhaS; Activates expression of the rhaBAD and rhaT operons
 
  
 0.820
araB
Ribulokinase; Escherichia coli K-12 ortholog: b0063; Escherichia coli O157:H7 ortholog: z0072; Belongs to the ribulokinase family
     
 0.777
araD
L-ribulose-5-phosphate 4-epimerase; Escherichia coli K-12 ortholog: b0061; Escherichia coli O157:H7 ortholog: z0069; Belongs to the aldolase class II family. AraD/FucA subfamily
     
 0.775
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L-fuculose
 
  
 0.737
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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