node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceB | gltA | c4971 | c0796 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | 0.978 |
aceB | mdh | c4971 | c3991 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.935 |
aceB | pckA | c4971 | c4176 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.908 |
aceB | ppc | c4971 | c4915 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.933 |
aceB | ppsA | c4971 | c2098 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.415 |
aceB | yojH | c4971 | c2751 | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | Malate:quinone oxidoreductase; Escherichia coli K-12 ortholog: b2210; Escherichia coli O157:H7 ortholog: z3468. | 0.915 |
eno | gltB | c3344 | c3973 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glutamate synthase [NADPH] large chain precursor; Escherichia coli K-12 ortholog: b3212; Escherichia coli O157:H7 ortholog: z4576. | 0.953 |
eno | mdh | c3344 | c3991 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.590 |
eno | pckA | c3344 | c4176 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.931 |
eno | ppc | c3344 | c4915 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.930 |
eno | ppsA | c3344 | c2098 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.930 |
eno | pykA | c3344 | c2268 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Pyruvate kinase II; Escherichia coli K-12 ortholog: b1854; Escherichia coli O157:H7 ortholog: z2906; Belongs to the pyruvate kinase family. | 0.984 |
eno | pykF | c3344 | c2071 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Pyruvate kinase I; Escherichia coli K-12 ortholog: b1676; Escherichia coli O157:H7 ortholog: z2704; Belongs to the pyruvate kinase family. | 0.987 |
gltA | aceB | c0796 | c4971 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family. | 0.978 |
gltA | gltB | c0796 | c3973 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Glutamate synthase [NADPH] large chain precursor; Escherichia coli K-12 ortholog: b3212; Escherichia coli O157:H7 ortholog: z4576. | 0.945 |
gltA | mdh | c0796 | c3991 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.992 |
gltA | pckA | c0796 | c4176 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.955 |
gltA | ppc | c0796 | c4915 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.978 |
gltA | ppsA | c0796 | c2098 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.444 |
gltA | yojH | c0796 | c2751 | Citrate synthase; Escherichia coli K-12 ortholog: b0720; Escherichia coli O157:H7 ortholog: z0873; Belongs to the citrate synthase family. | Malate:quinone oxidoreductase; Escherichia coli K-12 ortholog: b2210; Escherichia coli O157:H7 ortholog: z3468. | 0.956 |