STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
melRMelibiose operon Regulatory protein; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site (By similarity). (302 aa)    
Predicted Functional Partners:
araC
Arabinose operon Regulatory protein; Escherichia coli K-12 ortholog: b0064; Escherichia coli O157:H7 ortholog: z0073.
  
   
 0.886
rhaR
L-rhamnose operon transcriptional activator rhaR; Activates expression of the rhaSR operon in response to L- rhamnose.
 
 
 0.832
ykgD
Hypothetical transcriptional regulator ykgD; Escherichia coli K-12 ortholog: b0305; Escherichia coli O157:H7 ortholog: z0382.
  
     0.719
melA
Alpha-galactosidase; Escherichia coli K-12 ortholog: b4119; Escherichia coli O157:H7 ortholog: z5721.
 
   
 0.718
ypdC
Hypothetical transcriptional regulator ypdC; Escherichia coli K-12 ortholog: b2382; Escherichia coli O157:H7 ortholog: z3647.
  
   
 0.694
rhaS
L-rhamnose operon Regulatory protein rhaS; Activates expression of the rhaBAD and rhaT operons.
 
 
 0.680
cadC
Transcriptional activator cadC; Escherichia coli K-12 ortholog: b4133; Escherichia coli O157:H7 ortholog: z5736.
  
   
 0.646
ydiP
Hypothetical transcriptional regulator ydiP; Escherichia coli K-12 ortholog: b1696; Escherichia coli O157:H7 ortholog: z2724.
 
   0.577
soxS
Regulatory protein soxS; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity).
  
     0.575
marA
Multiple antibiotic resistance protein marA; Escherichia coli K-12 ortholog: b1531; Escherichia coli O157:H7 ortholog: z2170.
  
     0.558
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.