STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspAAspartate ammonia-lyase; Escherichia coli K-12 ortholog: b4139; Escherichia coli O157:H7 ortholog: z5744; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. (493 aa)    
Predicted Functional Partners:
ansA
Escherichia coli K-12 ortholog: b1767; Escherichia coli O157:H7 ortholog: z2801.
 
 
 0.954
ansB
L-asparaginase II precursor; Escherichia coli K-12 ortholog: b2957; Escherichia coli O157:H7 ortholog: z4302; Belongs to the asparaginase 1 family.
 
 
 0.952
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.917
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.916
argH
Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518.
     
0.910
ybiK
Putative L-asparaginase precursor; Escherichia coli K-12 ortholog: b0828; Escherichia coli O157:H7 ortholog: z1052.
    
 0.906
purB
Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860.
     
 0.906
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.906
asnB
Asparagine synthetase B (glutamine-hydrolyzing); Escherichia coli K-12 ortholog: b0674; Escherichia coli O157:H7 ortholog: z0821.
     
 0.903
aspC
Aspartate aminotransferase; Escherichia coli K-12 ortholog: b0928; Escherichia coli O157:H7 ortholog: z1275.
     
  0.900
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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