STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ytfPHypothetical protein ytfP; Escherichia coli K-12 ortholog: b4222; Escherichia coli O157:H7 ortholog: z5833; Belongs to the gamma-glutamylcyclotransferase family. (113 aa)    
Predicted Functional Partners:
ytfM
Hypothetical protein ytfM precursor; Escherichia coli K-12 ortholog: b4220; Escherichia coli O157:H7 ortholog: z5831.
 
   
 0.907
ytfN
Hypothetical protein ytfN; Escherichia coli K-12 ortholog: b4221; Escherichia coli O157:H7 ortholog: z5832.
 
   
 0.846
ybgE
Protein ybgE; Escherichia coli K-12 ortholog: b0735; Escherichia coli O157:H7 ortholog: z0903.
  
     0.618
yecF
Hypothetical protein yecF; Escherichia coli K-12 ortholog: b1915; Escherichia coli O157:H7 ortholog: z3003.
  
     0.613
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
       0.585
yhiO
Universal stress protein B; Escherichia coli K-12 ortholog: b3494; Escherichia coli O157:H7 ortholog: z4894.
  
     0.578
pqqL
Probable zinc protease pqqL; Escherichia coli K-12 ortholog: b1494; Escherichia coli O157:H7 ortholog: z2214; Belongs to the peptidase M16 family.
      
 0.564
yaeT
Unknown protein from 2D-page spots M62/M63/O3/O9/T35 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
     
 0.563
ydgH
Protein ydgH precursor; Escherichia coli K-12 ortholog: b1604; Escherichia coli O157:H7 ortholog: z2603.
  
     0.557
surA
Survival protein surA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
     
 0.556
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.