STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
celIGlycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (887 aa)    
Predicted Functional Partners:
celS
Glycoside hydrolase family 48; This enzyme catalyzes the exohydrolysis of 1,4-beta- glucosidic linkages in cellulose with a preference for amorphous or crystalline cellulose over carboxymethyl cellulose.
 
   0.979
Cthe_0405
PFAM: glycoside hydrolase family 5; Dockerin type 1; KEGG: csc:Csac_1078 cellulose 1,4-beta-cellobiosidase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
 0.865
celB
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
 0.852
bglA
TIGRFAM: beta-galactosidase; KEGG: dtu:Dtur_1799 beta-galactosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
     
 0.826
Cthe_0071
KEGG: cpy:Cphy_3368 cellulose 1,4-beta-cellobiosidase; PFAM: glycoside hydrolase family 48; type 3a cellulose-binding domain protein.
 
 
  
0.806
celE
Glycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
 
 
 0.803
xghA
Dockerin type 1; Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose (By similarity).
 
   
 0.774
Cthe_0275
PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: cce:Ccel_2109 glycosyltransferase 36.
     
 0.762
celG
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
 0.739
Cthe_0821
PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase family 5; Dockerin type 1; KEGG: cce:Ccel_0379 protein of unknown function DUF291; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
   
 0.667
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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