STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0083Protein serine/threonine phosphatase; KEGG: amt:Amet_1030 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein. (559 aa)    
Predicted Functional Partners:
Cthe_2898
KEGG: ate:Athe_0435 anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
 
 
 0.910
Cthe_1825
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
  
 0.897
Cthe_2163
KEGG: ddf:DEFDS_0429 anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.867
Cthe_2901
PFAM: ATP-binding region ATPase domain protein; KEGG: ate:Athe_2394 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.822
Cthe_2899
KEGG: cce:Ccel_0399 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.785
Cthe_0408
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; extracellular solute-binding protein family 3; PAS fold domain protein; GGDEF domain containing protein; KEGG: diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3.
 
  
 0.713
Cthe_2622
PFAM: Flagellar protein FlgJ-like; KEGG: cce:Ccel_3099 hypothetical protein.
  
    0.694
Cthe_2189
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: hya:HY04AAS1_1171 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein.
 
  
 0.679
Cthe_0806
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; KEGG: swo:Swol_1328 signal transduction histidine kinase-like protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein.
  
 0.661
Cthe_2900
KEGG: ate:Athe_0437 RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein.
 
 
 0.659
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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